盘基网柄菌发育过程中的细胞间信号传导。
Cell-cell signaling during Dictyostelium development.
作者信息
Söderbom F, Loomis W F
机构信息
Dept of Biology, University of California San Diego, La Jolla 92093, USA.
出版信息
Trends Microbiol. 1998 Oct;6(10):402-6. doi: 10.1016/s0966-842x(98)01348-1.
PMID:9807784
Abstract
Specific proteins and peptides, as well as cAMP, are used as intercellular signals in Dictyostelium. Our understanding of the signal transduction pathways activated by these signals has been expanded by inclusion of newly characterized proteins. cAMP-dependent protein kinase (PKA) and its associated phosphodiesterase, RegA, play multiple roles in these pathways.
摘要
在盘基网柄菌中，特定的蛋白质和肽以及环磷酸腺苷（cAMP）被用作细胞间信号。通过纳入新鉴定的蛋白质，我们对这些信号激活的信号转导途径的理解得到了扩展。cAMP依赖性蛋白激酶（PKA）及其相关的磷酸二酯酶RegA在这些途径中发挥多种作用。
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