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[孕期自体血采集与胎儿安全。胎儿心率的计算机分析]

[Collection of autologous blood during pregnancy and fetal safety. Computer analysis of fetal heart rate].

作者信息

Rech F, Indraccolo S R, Cecchi A, Patella A

机构信息

Scuola Autonoma di Ostetricia, Camerino (Macerata), Università degli Studi di Roma La Sapienza.

出版信息

Minerva Ginecol. 1998 Jul-Aug;50(7-8):313-9.

PMID:9808955
Abstract

BACKGROUND

This study aims at objectively evaluating the impact on the fetus of a sudden maternal blood withdrawal, through a computer analysis of the various aspects of the cardiotocographic pattern before and after one autologous blood unit predonation from near term pregnant women.

METHODS

For the collection of cardiotocographic data, a Sonicaid Team fetal monitor was used; it is a monitoring system which uses Doppler ultrasound impulses and autocorrelates the received Doppler signals with varied signals of frequency, connected to Sonicaid System 8000, a program for "objective" cardiotocographic analysis according to the so-called Dawes-Redman criteria.

RESULTS

From the statistic comparison of Non Stress Tests preceeding and following predonation, some statistically significant differences have sometimes emerged on the level of specific parameters.

CONCLUSIONS

In particular, the general variation of fetal heart frequency and fetal reactivity resulted higher after predonation, even though they were within absolute normality, justifying the suspicion that the stress of autologous predonation practice might produce some indefinite disturbance to fetal activity/rest rhythm.

摘要

背景

本研究旨在通过对近期孕妇自体捐献一个单位血液前后胎心监护图各方面进行计算机分析,客观评估孕妇突然失血对胎儿的影响。

方法

为收集胎心监护数据,使用了Sonicaid Team胎儿监护仪;它是一种利用多普勒超声脉冲并将接收到的多普勒信号与不同频率信号进行自相关分析的监测系统,连接到Sonicaid System 8000,这是一个根据所谓的道斯 - 雷德曼标准进行“客观”胎心监护分析的程序。

结果

通过对献血前后无应激试验的统计比较,有时在特定参数水平上出现了一些具有统计学意义的差异。

结论

特别是,尽管胎儿心率和胎儿反应性的总体变化仍在绝对正常范围内,但献血后这些变化更高,这表明有理由怀疑自体献血操作带来的应激可能会对胎儿活动/休息节律产生一些不确定的干扰。

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