Chignon J M, Cortes M J, Martin P, Chabannes J P
Centre Hospitalier de la Région Annecienne, Unité de Soins Spécialisés, Annecy.
Encephale. 1998 Jul-Aug;24(4):347-54.
The relationship between alcoholism and suicidal behaviour has long been recognized. The present study examined the lifetime prevalence of suicide attempts in alcoholic patients and the impact of comorbidity, namely with depressive anxiety disorders and antisocial personnalit disorder in alcoholic patients who attempted suicide.
In a cross-sectional design including outpatients referring for alcohol dependance according to DSM III-R criteria, we used a specific standardized and structured interview allowing DSM III-R diagnoses.
We include 507 patients (343 males of 164 females). The mean age at the intake of the study was 43.2 (SD:9.6) years without difference between males and females. 129 patients (25.4%) had attempted suicide during their lifetime. The proportion of female was found higher than males among suicide attempters (41.9 vs 29.3%; p < or = 0.001). Age of onset of alcoholism was found younger in suicide attempters than non (p < or = 0.01), either in males and females. Moreover, we found that alcoholic suicide attempters more often reported family histories of alcoholism than did nonattempters. As regard lifetime comorbidity, major depression and drugs misuse were found more frequent in alcoholics who attempted suicide (p < or = 0.001). Moreover, we found a higher prevalence for Panic Disorder and Social Phobia in male suicide attempters.
酗酒与自杀行为之间的关系早已为人所知。本研究调查了酒精性患者自杀未遂的终生患病率,以及合并症的影响,即对有自杀未遂行为的酒精性患者中抑郁焦虑障碍和反社会人格障碍的影响。
在一项横断面设计中,纳入了根据DSM III-R标准因酒精依赖前来就诊的门诊患者,我们使用了一种特定的标准化结构化访谈来进行DSM III-R诊断。
我们纳入了507名患者(343名男性和164名女性)。研究纳入时的平均年龄为43.2岁(标准差:9.6),男性和女性之间无差异。129名患者(25.4%)终生有过自杀未遂行为。在自杀未遂者中,女性比例高于男性(41.9%对29.3%;p≤0.001)。无论是男性还是女性,自杀未遂者的酗酒发病年龄都比未自杀未遂者年轻(p≤0.01)。此外,我们发现酗酒自杀未遂者比未自杀未遂者更常报告有酗酒家族史。关于终生合并症,在自杀未遂的酒精性患者中,重度抑郁症和药物滥用更为常见(p≤0.001)。此外,我们发现男性自杀未遂者中惊恐障碍和社交恐惧症的患病率更高。