Déchaud H, Ferron G, Anahory T, Arnal F, Humeau C, Hédon B
Service de Gynécologie-Obstétrique, CHU Arnaud de Villeneuve, Faculté de Médecine de Montpellier.
Contracept Fertil Sex. 1998 Jul-Aug;26(7-8):564-7.
Obesity was defined by a body mass index more than 30 kg/m2. Many risks were related to this pathology, and sometimes, menstrual disorders or infertility. In order to obtain an adequate response to ovarian stimulation during IVF cycles, higher doses of menotropins are necessary in the group of obese patients. The mechanism of this phenomenon is still unclear. Leptin is one of the main hypothesis, and could act on obesity and reproductive system simultaneously. The likelihood to have an ongoing pregnancy after IVF treatment is less in the group of obese patients because of the increased risk of miscarriage and obstetrical complications. Weight loss prior IVF remains the main advice in order to decrease the risks of the procedure and to treat successfully these patients.