Veiga A, Boada M, Barri P N
Dpt. Obst. Gynec., Institut Universitari Dexeus, Barcelona, Spain.
Contracept Fertil Sex. 1998 Jul-Aug;26(7-8):568-72.
The combination of the technique of In Vitro Fertilization (IVF) and molecular genetics has led to the development of Preimplantation Genetic Diagnosis (PGD). Oocyte and embryo biopsy, Fluorescent in situ Hybridization (FISH) and Polymerase Chain Reaction (PCR) allow diagnostic procedures in couples with high risk and also certain IVF couples. We present a review of PGD indications, techniques and results.
体外受精（IVF）技术与分子遗传学的结合导致了植入前基因诊断（PGD）的发展。卵母细胞和胚胎活检、荧光原位杂交（FISH）和聚合酶链反应（PCR）使高危夫妇以及某些体外受精夫妇能够进行诊断程序。我们对植入前基因诊断的适应症、技术和结果进行综述。
