Purdy J A, Harms W B
Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Strahlenther Onkol. 1998 Oct;174 Suppl 2:2-7.
Three-dimensional conformal radiation therapy (3D CRT) can be considered as an integrated process of treatment planning, delivery, and verification that attempts to conform the prescription dose closely to the target volume while limiting dose to critical normal structures. Requiring the prescription dose to conform as closely as possible to the target volume raises the level of the precision and accuracy requirements generally found in conventional radiation therapy. 3D CRT treatment planning requires robust patient immobilization/repositioning systems and volumetric image data (CT and/or MR) acquired in the treatment position. 3D treatment planning more explicitly details the particulars of a patient's treatment than was ever possible with 2D treatment planning. In 1992, we implemented a formal 3D treatment planning service in our clinic and at that same time instituted a formal quality assurance (QA) program addressing the individual procedures that make up the 3D CRT process. Our 3D QA program includes systematic testing of the hardware and software used in the 3D treatment planning process, careful review of each patient's treatment plan, careful review of the physical implementation of the treatment plan, a peer review 3D QA Case Conference, and a formal continuing education program in 3D CRT for our radiation therapy staff. This broad 3D QA program requires the involvement of physicians, physicists, dosimetrists, and the treating radiation therapists that complete the team responsible for 3D CRT. 3D CRT capabilities change the kinds of radiation therapy treatments that are possible and that changes the process with which treatment planning and treatment delivery are performed. There is no question that 3D CRT shows significant potential for improving the quality of radiation therapy and improving the efficiency with which it can be delivered. However, its implementation and wide spread use is still in its initial stages. The techniques used for 3D treatment planning and the associated QA procedures and tests should still be considered developmental and changes are likely to continue to occur over the next several years.
三维适形放射治疗(3D CRT)可被视为一个包括治疗计划、实施和验证的综合过程,该过程试图使处方剂量紧密贴合靶区体积,同时将对关键正常组织的剂量限制在一定范围内。要求处方剂量尽可能贴合靶区体积,这提高了常规放射治疗中通常所需的精度和准确性水平。3D CRT治疗计划需要可靠的患者固定/重新定位系统以及在治疗体位获取的容积图像数据(CT和/或MR)。与二维治疗计划相比,三维治疗计划更明确地详细说明了患者治疗的具体情况。1992年,我们在诊所实施了正式的三维治疗计划服务,同时制定了一项正式的质量保证(QA)计划,涵盖构成3D CRT过程的各个程序。我们的3D QA计划包括对3D治疗计划过程中使用的硬件和软件进行系统测试,仔细审查每位患者的治疗计划,仔细审查治疗计划的实际实施情况,举行同行评审3D QA病例会议,以及为我们的放射治疗人员开展关于3D CRT的正式继续教育项目。这个广泛的3D QA计划需要医生、物理学家、剂量师以及完成3D CRT治疗团队工作的放射治疗师的参与。3D CRT技术改变了可能的放射治疗方式,也改变了治疗计划和治疗实施的过程。毫无疑问,3D CRT在提高放射治疗质量和提高放射治疗实施效率方面显示出巨大潜力。然而,其实施和广泛应用仍处于初始阶段。用于三维治疗计划的技术以及相关的QA程序和测试仍应被视为尚在发展中,并且在未来几年可能会继续发生变化。