Juárez U, Trejo W, Whente M, Contreras G, Cárdenas M, Reyes P A
Unidad Coronaria, Instituto Nacional de Cardiología Ignacio Chávez, México, D.F.
Arch Inst Cardiol Mex. 1998 May-Jun;68(3):214-7.
Diagnosis of acute myocardial infarction is made with the aid of biomarkers such as structural myocardial proteins, myoglobin (MG) or specific enzymes, creatine phosphokinase isoenzyme MB (CK-MB) or non specific enzymes, lactic dehydrogenase (DHL) and aspartate aminotransferase (AST). We found good sensitivity (71%-50%), specificity (85%-100%) and predictive values (Pos. 77%-100%, Neg. 82%-72%) for Mg and CK-MB, supporting their clinical usefulness. In contrast DHL and AST were not clinically useful for early diagnosis.
急性心肌梗死的诊断借助生物标志物进行,如心肌结构蛋白、肌红蛋白(MG)或特定酶,肌酸磷酸激酶同工酶MB(CK-MB)或非特异性酶,乳酸脱氢酶(DHL)和天冬氨酸转氨酶(AST)。我们发现Mg和CK-MB具有良好的敏感性(71%-50%)、特异性(85%-100%)和预测值(阳性77%-100%,阴性82%-72%),支持它们的临床实用性。相比之下,DHL和AST对早期诊断无临床实用性。