Schricker K T, Kluge R
Prakt Anaesth. 1976 Oct;11(5):303-9.
During February 1973 to October 1974 950 inpatients of the Department of Surgery, Erlangen, were tested for the presence of iso-antibodies before and after blood transfusions. Irregular antibodies were demonstrable in 0.95% of the patients before they received a blood transfusion. In 2.73% of the cases blood transfusion resulted in sensitization with the formation of specific blood group antibodies. Identification of the 26 iso-antibodies showed a prevalence of anti-Kell and anti-E (7 cases each). In view of the frequent occurrence of these two antigens tests for their presence are advisable before a blood transfusion is given. Persons who are re-admitted to hospital should also be tested to the presence of irregular antibodies to ensure that sensitization has not occurred during the intervening period.
1973年2月至1974年10月期间,埃尔朗根外科部的950名住院患者在输血前后接受了同种抗体检测。在接受输血前,0.95%的患者可检测到不规则抗体。在2.73%的病例中,输血导致致敏并形成特异性血型抗体。对这26种同种抗体的鉴定显示,抗凯尔抗体和抗-E抗体最为常见(各7例)。鉴于这两种抗原经常出现,建议在输血前检测其是否存在。再次入院的患者也应检测是否存在不规则抗体,以确保在此期间未发生致敏。