Geies A A, Bakhite E A, el-Kashef H S
Chemistry Department, Faculty of Science, Assiut University, Egypt.
Pharmazie. 1998 Oct;53(10):686-90.
2-Acetyl-4-(p-chlorophenyl)-3-(1-pyrrolyl)-5,6,7,8- tetrahydrothieno[2,3-b]quinoline (4a) and its corresponding 2-carbohydrazide derivative 5 were prepared and used as key intermediates in the synthesis of the title compounds. Some of the synthesized compounds were screened for their antibacterial and antifungal activities.
2-乙酰基-4-(对氯苯基)-3-(1-吡咯基)-5,6,7,8-四氢噻吩并[2,3-b]喹啉(4a)及其相应的2-碳酰肼衍生物5被制备出来,并用作合成目标化合物的关键中间体。对一些合成化合物进行了抗菌和抗真菌活性筛选。