Li J, Sun S, Xue L
304th Hospital of People's Liberation Army, Beijing.
Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi. 1997 Jan;13(1):40-2.
We invistigated the sequntial changes in plasma and intestinal diamine oxidase (DAO) levels in animals and patients after burn injury. The results were as follows: 1. The plasma DAO level in patients was increased significantly at 1, 3, 7, 14 d and returned to normal at 21 d postburn; 2. In pigs, the elevation of plasma DAO level was also found during the whole experiment, but only significantly so at 72 h postburn; 3. In scald rats, the DAO level was increased in plasma and decreased in intestine. The above results suggested that intestinal mucosa injury and DAO release into blood occurred after burn injury. The activity of DAO in plasma might be one of the marker to reflect injury of intestinal mucosa.
我们研究了烧伤后动物和患者血浆及肠道中二胺氧化酶（DAO）水平的动态变化。结果如下：1. 患者血浆DAO水平在烧伤后1、3、7、14天显著升高，在烧伤后21天恢复正常；2. 在猪中，整个实验过程中血浆DAO水平也升高，但仅在烧伤后72小时显著升高；3. 在烫伤大鼠中，血浆中DAO水平升高，肠道中DAO水平降低。上述结果表明，烧伤后发生了肠黏膜损伤以及DAO释放入血。血浆中DAO的活性可能是反映肠黏膜损伤的标志物之一。
