[1972 - 1991年中国肝癌高发区启东原发性肝癌的基于人群的生存分析]

[Population-based survival analysis of primary liver cancer in a high-incidence area-Qidong, China during 1972-1991].

作者信息

Chen J, Sankaranrayanan R, Li W

机构信息

Qidong Institute of Liver Cancer Qidong, Jiangsu.

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 1997 May;31(3):149-52.

PMID:9812592

Abstract

Population-based survival and relative survival of primary liver-cancer (PLC) were analyzed for 11,200 cases in an area with high-incidence, Qidong, Jiangsu Province, during 1972 to 1991. Results showed that observed survival was 2.1% and 2.0% in the first (1972-1981) and the second ten years (1982-1991), respectively, and relative survival 2.2% and 2.3%, respectively. Females had more favorable survival than did males, with five-year survival of 3.5% and 1.7% in the first ten years, respectively, and 2.6% and 1.8% in the second ten years, respectively, but without statistical significance in their difference. No significant difference in age groups was found during 1982 to 1991, with five-year survival of 2.2%, 1.9%, 1.3%, 2.2% and 1.5% for males, and 3.7%, 3.1%, 2.8%, 2.1% and 2.6% for females, and with five-year relative survival of 2.2%, 1.95%, 1.4%, 2.4% and 1.9% for males, and 3.7%, 3.1%, 2.9%, 2.2%, and 3.0% for females, in 0-34, 35-44, 45-54, 55-64 and 65-over age groups, respectively. It indicated that prognosis of PLC was poor in Qidong, and it is urgent to screen for PLC in high risk population, to detect it earlier, to manage it with adequate measures, and to improve its survival.

摘要

对江苏省启东市这个肝癌高发地区1972年至1991年间的11200例原发性肝癌（PLC）患者进行了基于人群的生存率和相对生存率分析。结果显示，在第一个十年（1972 - 1981年）和第二个十年（1982 - 1991年），观察到的生存率分别为2.1%和2.0%，相对生存率分别为2.2%和2.3%。女性的生存率比男性更优，在第一个十年中五年生存率分别为3.5%和1.7%，在第二个十年中分别为2.6%和1.8%，但两者差异无统计学意义。1982年至1991年间各年龄组无显著差异，0 - 34岁、35 - 44岁、45 - 54岁、55 - 64岁和65岁以上年龄组男性的五年生存率分别为2.2%、1.9%、1.3%、2.2%和1.5%，女性分别为3.7%、3.1%、2.8%、2.1%和2.6%；男性的五年相对生存率分别为2.2%、1.95%、1.4%、2.4%和1.9%，女性分别为3.7%、3.1%、2.9%、2.2%和3.0%。这表明启东市原发性肝癌的预后较差，迫切需要在高危人群中筛查原发性肝癌，尽早发现，采取适当措施进行治疗，以提高其生存率。