Zharskaya V D, Chukhlovin A B
Primorsky Health Rehabilitation Center, St. Petersburg, Russia.
Scanning Microsc. 1996;10(1):279-83; discussion 283-4.
Scanning electron microscopy (SEM) of red blood cells in whole blood samples from rats was performed following acute gamma-irradiation of animals with 0.25 to 1 Gy. Increased incidence of echinocytosis was observed and found to be dose- and time-dependent. At a higher radiation dose (1 Gy), echinocytosis was revealed within 5 minutes after treatment and persisted up to 3 weeks. The data demonstrate the applicability of SEM for detecting minimal radiation-induced lesions of red blood cells.
在用0.25至1 Gy对大鼠进行急性γ射线照射后，对大鼠全血样本中的红细胞进行了扫描电子显微镜（SEM）检查。观察到棘形红细胞增多症的发生率增加，且发现其与剂量和时间有关。在较高辐射剂量（1 Gy）下，治疗后5分钟内即出现棘形红细胞增多症，并持续长达3周。这些数据证明了扫描电子显微镜在检测红细胞最小辐射诱导损伤方面的适用性。
