Funaba M, Hashimoto E, Iriki T, Abe M
Department of Nutrition, School of Veterinary Medicine, Azabu University, Sagamihara, Japan.
Exp Anim. 1998 Jul;47(3):143-9. doi: 10.1538/expanim.47.143.
Five male cats were used to examine utilization of nitrogen and macro-minerals (calcium, phosphorus and magnesium) in response to food restriction and subsequent repletion. For the first week, each cat was daily given 135 g of dry cat food (baseline period), followed by a restriction period for 1 week; during this period, daily food was individually restricted to 40% of the amount consumed by each cat during the baseline period. Food provision was then returned to the daily 135 g for the final week (recovery period). Fecal weight changed in association with changes in daily food intake, but urine volume changed less with the periods. Fecal and urinary excretion of nitrogen rapidly decreased during the restriction period, but the decreases were smaller than the decrease in nitrogen intake, leading to net nitrogen loss. On the other hand, the food restriction had relatively smaller effects on retention of macro-minerals, and calcium retention was not significantly affected by daily food provision, although the plasma concentration of magnesium was increased during the restriction period and tended to return during the recovery period. Nitrogen retention was increased by the removal of food restriction, but did not exceed the original level of nitrogen retention during the baseline period. These findings suggested that restriction of diet had a serious effect on nitrogen balance, and the impaired protein nutrition might not be easily recovered by subsequent nutritional repletion.
选用5只雄性猫来研究限食及随后再投喂情况下氮和常量矿物质（钙、磷和镁）的利用情况。在第一周，每只猫每天给予135克干猫粮（基线期），随后是1周的限食期；在此期间，每天的食物量分别限制为每只猫在基线期消耗量的40%。然后在最后一周将食物供应量恢复到每天135克（恢复期）。粪便重量随每日食物摄入量的变化而变化，但尿量随各时期变化较小。限食期内粪便和尿液中的氮排泄迅速减少，但减少幅度小于氮摄入量的减少幅度，导致氮净损失。另一方面，食物限制对常量矿物质潴留的影响相对较小，尽管限食期血浆镁浓度升高，恢复期有恢复趋势，但每日食物供应量对钙潴留无显著影响。去除食物限制后氮潴留增加，但未超过基线期氮潴留的原始水平。这些发现表明，饮食限制对氮平衡有严重影响，蛋白质营养受损可能不易通过随后的营养补充恢复。
