Krivoshchekov S G, Roĭfman M D, Divert G M, Kovtun L E, Platonov Ia G, Velichko I L
Vestn Ross Akad Med Nauk. 1998(9):48-53.
Respiratory and circulatory changes in response to various physiological stimuli (hypoxia, cold, etc.) were studied. The respiratory center was found to play the leading role in the developing a response. Upon repeated exposures to cold and hypoxia, the central regulatory mechanisms include nonspecific compensatory mechanisms by changing the sensitivity of the respiratory center and its thresholds. Various regulatory strategies were found at different stages of adaptive processes. There was a correlation between the changes in the respiratory center and thermoregulatory shifts. The respiratory center was demonstrated to play a system-forming role. It is suggested that determination of the sensitivity of the respiratory center may serve for prognostic and diagnostic purposes.
研究了机体对各种生理刺激（缺氧、寒冷等）的呼吸和循环变化。发现呼吸中枢在产生反应过程中起主导作用。在反复暴露于寒冷和缺氧环境时，中枢调节机制包括通过改变呼吸中枢的敏感性及其阈值的非特异性代偿机制。在适应性过程的不同阶段发现了各种调节策略。呼吸中枢的变化与体温调节变化之间存在相关性。已证明呼吸中枢起系统形成作用。建议测定呼吸中枢的敏感性可用于预后和诊断目的。
