Chaler R, Vilanova R, Santiago-Silva M, Fernandez P, Grimalt J O
Department of Environmental Chemistry (CID-CSIC), Barcelona, Catalonia, Spain.
J Chromatogr A. 1998 Oct 9;823(1-2):73-9. doi: 10.1016/s0021-9673(98)00516-0.
A comparison of the performances of ammonia and methane as reagent gases for the analysis of trace organochlorine compounds by gas chromatography coupled to negative-ion chemical ionization mass spectrometry is performed in the present study. Examples of standard mixtures and human blood samples analyzed with both reagents in scan and selected-ion monitoring mode are shown. Important advantages are observed as a consequence of the use of ammonia. These concern detection and quantitation limits and the lower dependence of sensitivity on the degree of chlorine substitution of the compounds.
本研究对氨和甲烷作为试剂气体，用于气相色谱-负离子化学电离质谱联用分析痕量有机氯化合物的性能进行了比较。展示了在扫描和选择离子监测模式下，使用这两种试剂分析标准混合物和人体血液样本的示例。使用氨的结果显示出重要优势。这些优势涉及检测限和定量限，以及灵敏度对化合物氯取代程度的较低依赖性。
