Makins A E, Nikolopoulos T P, Ludman C, O'Donoghue G M
Department of Academic Radiology, University Hospital, Queen's Medical Centre NHS Trust, Nottingham, United Kingdom.
Laryngoscope. 1998 Nov;108(11 Pt 1):1739-42. doi: 10.1097/00005537-199811000-00027.
To assess whether contact of a vascular loop formed by the anterior inferior cerebellar artery (AICA) with the eighth cranial nerve correlated with unilateral auditory symptoms so as to produce a "vascular compression syndrome."
Prospective evaluation of patients with unilateral auditory symptoms using magnetic resonance imaging (MRI) scans to identify contact of a vascular loop with the eighth cranial nerve.
One hundred twelve patients with idiopathic unilateral auditory symptoms (42 women and 70 men, mean age of 51 years) were evaluated with MRI. Location of the vascular loop and contact with the eighth cranial nerve were assessed in each case. The asymptomatic contralateral ears of the patients were used as controls. A power analysis had determined the size of the sample to be studied.
The arterial loop was found to be in contact with the eighth cranial nerve in 28 (25%) of the 112 symptomatic ears and in 24 (21.4%) of the asymptomatic (control) ears. The statistical analysis revealed that the difference was not statistically significant.
The results suggest that radiologic demonstration of contact between a vascular loop formed by the AICA and the eighth cranial nerve on MRI scans should be considered a normal anatomic finding and should not, on its own, be used to support the diagnosis of a "vascular compression syndrome."
评估由小脑下前动脉（AICA）形成的血管袢与第八颅神经的接触是否与单侧听觉症状相关，从而产生“血管压迫综合征”。
对有单侧听觉症状的患者进行前瞻性评估，使用磁共振成像（MRI）扫描来确定血管袢与第八颅神经的接触情况。
对112例特发性单侧听觉症状患者（42例女性和70例男性，平均年龄51岁）进行MRI评估。评估每个病例中血管袢的位置以及与第八颅神经的接触情况。将患者无症状的对侧耳作为对照。一项功效分析确定了要研究的样本量。
在112例有症状的耳中，有28例（25%）发现动脉袢与第八颅神经接触，在无症状（对照）耳中有24例（21.4%）发现这种接触。统计分析显示差异无统计学意义。
结果表明，MRI扫描显示AICA形成的血管袢与第八颅神经之间的接触应被视为正常的解剖学发现，其本身不应被用于支持“血管压迫综合征”的诊断。
