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一名接受四氧化锇治疗的医生患耶尔森菌感染后反应性关节炎。

Post-yersinotic Reiter's disease in a physician treated with osmium tetroxide.

作者信息

Bakken A F, Blichfeldt P

出版信息

Scand J Rheumatol. 1976;5(3):174-6. doi: 10.3109/03009747609165458.

Abstract

A case of general yersinosis in a male physician is described. Most probably the infection was acquired nosocomially in a paediatric ward. The infection affected several organs including the liver, but osmium tetroxide was nevertheless used to perform chemical synovectomy in a knee joint suffering from active arthritis. The arthritis was cured, and the already existing liver affection did not progress. The only complaint from the patient, months after the osmic acid injection, was a strong metallic taste on the tongue. More than a year after the intra-articular injection, the metallic taste disappeared. The amount of osmium in the patient's blood was then calculated to be less than 100 molecules of osmium per ml blood.

摘要

描述了一名男性医生患全身性耶尔森菌病的病例。感染很可能是在儿科病房医院获得性感染。感染累及包括肝脏在内的多个器官,但尽管如此,仍使用四氧化锇对患有活动性关节炎的膝关节进行化学滑膜切除术。关节炎治愈,已有的肝脏病变未进展。在注射锇酸数月后,患者唯一的主诉是舌头上有强烈的金属味。关节内注射一年多后,金属味消失。当时计算出患者血液中的锇含量低于每毫升血液100个锇分子。

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