Locher G W, Grétillat P A, Herrmann U
Schweiz Med Wochenschr. 1976 Apr 10;106(15):517-21.
Smears from the uterine cervix have been evaluated for neoplastic changes on the basis of descriptive terms. The material was obtained by a single gynecologist using a standardized sampling technique and the results were compared with the respective histological diagnoses. Material which was found to be unsuitable for technical reasons was excluded from this study. A 98.7% agreement between cytological and histological findings was noted. Discrepancies between cytological and histological findings were essentially due to differing dysplastic changes in the deeper layers of the surface epithelium and the cervical glands, which were not sampled by the smears on the surface layer. In a few cases the discrepancies could not be explained but they disappeared after several years of observation. The practitioner should be acquainted with the nomenclature used by cytologists. In his turn, the cytologist should be familiar with the pathological anatomy of the organ in question.
宫颈涂片已根据描述性术语对肿瘤性变化进行了评估。材料由一位妇科医生采用标准化采样技术获取,并将结果与各自的组织学诊断进行比较。因技术原因被判定为不合适的材料被排除在本研究之外。细胞学和组织学检查结果之间的一致性为98.7%。细胞学和组织学检查结果之间的差异主要是由于表层上皮和宫颈腺深层发育异常变化不同,而涂片未对表层进行采样。在少数情况下,差异无法解释,但经过数年观察后消失了。从业者应熟悉细胞学家使用的命名法。反过来,细胞学家也应熟悉所讨论器官的病理解剖学。