Dítĕ P, Hep A, Dolina J, Sevcíková A, Novotný I, Stroblová H, Kunovská M, Münzová H, Pokorný A
III. interní-gastroenterologická klinika FN MU, Brno-Bohunice.
Vnitr Lek. 1998 Mar;44(3):132-4.
The prevalence of Helicobacter pylori is influenced in a significant way by geographical conditions and depends to a certain extent also on the economic standard of different countries. Some published work provides evidence that Helicobacter pylori infections in eastern European countries are in general more frequent than in western European countries. It cannot be ruled out, however, that in different countries there are regional differences as far as Helicobacter pylori is concerned. In a group of 309 subjects, none of those treated previously to eradicate H.pylori, at least three weeks before blood sampling no preparations of the type of H2 blockers, proton pump blockers or drugs containing bismuth were administered. In these patients serological examinations of H.pylori antibodies were made, using kits of TEST-LINE Brno. The examined subjects were divided into six age groups by decades, starting at the age of 20 years. The general prevalence of H.pylori in the examined group was 58.8%, in the group of 20-year-old ones less than 46%. The highest prevalence was recorded in subjects aged 50-59 years and amounted to 67.3%. The authors compare their own results with findings assembled in the Czech Republic and abroad and draw attention to the necessity of an extensive epidemiological survey of H.pylori prevalence in the Czech Republic. The survey should be done by regions, using the same diagnostic method.
幽门螺杆菌的流行率受地理条件的显著影响，在一定程度上也取决于不同国家的经济水平。一些已发表的研究表明，东欧国家幽门螺杆菌感染总体上比西欧国家更为常见。然而，不能排除在不同国家，就幽门螺杆菌而言存在地区差异。在一组309名受试者中，在采血前至少三周，之前接受过根除幽门螺杆菌治疗的人中，没有一人服用过H2阻滞剂、质子泵阻滞剂或含铋药物。在这些患者中，使用布尔诺TEST-LINE试剂盒进行了幽门螺杆菌抗体的血清学检测。受检者按十年分为六个年龄组，从20岁开始。受检组中幽门螺杆菌的总体流行率为58.8%，20岁组低于46%。50 - 59岁的受试者中幽门螺杆菌流行率最高，达67.3%。作者将他们自己的结果与在捷克共和国和国外收集的研究结果进行了比较，并提请注意在捷克共和国对幽门螺杆菌流行率进行广泛流行病学调查的必要性。该调查应按地区进行，采用相同的诊断方法。
