Tennstedt C, Chaoui R, Bollmann R, Körner H, Dietel M
Department of Pathology, Charité Hospital, Humboldt University, Berlin, Germany.
Pathol Res Pract. 1998;194(10):721-4. doi: 10.1016/S0344-0338(98)80132-5.
The findings of prenatal ultrasound diagnosis were compared with the autopsy findings in 183 fetuses (between the 14th and 24th week of gestation), aborted for fetal malformations in the period from 1995 to 1997. In these 183 cases, the primary diagnosis showed 50 central nervous system anomalies, 48 cardiovascular system anomalies, 42 genitourinary system anomalies, 18 respiratory system anomalies, 8 skeleton system anomalies, 6 gastrointestinal system anomalies and 11 other abnormalities. Of the total number of cases, 41% had multiple malformations. In 144 cases (78%), the prenatal diagnosis was confirmed by autopsy, in 36 cases (20%) the prenatal diagnosis was confirmed with additional significant pathology, and in only 3 cases (2%) the prenatally detected malformation was not confirmed by pathological examination. Autopsy remains an important component of the evaluation of fetal losses after induced abortion.
对1995年至1997年期间因胎儿畸形而流产的183例胎儿（妊娠14至24周）的产前超声诊断结果与尸检结果进行了比较。在这183例病例中，初步诊断显示50例中枢神经系统异常、48例心血管系统异常、42例泌尿生殖系统异常、18例呼吸系统异常、8例骨骼系统异常、6例胃肠道系统异常以及11例其他异常。在所有病例中，41%有多种畸形。144例（78%）的产前诊断经尸检证实，36例（20%）的产前诊断经额外的重要病理学检查证实，只有3例（2%）产前检测到的畸形未得到病理检查的证实。尸检仍然是人工流产后胎儿损失评估的重要组成部分。
