Campos M, Takahashi R, Tanaka H, Chamon W, Allemann N
Department of Ophthalmology, Federal University of São Paulo, Paulista School of Medicine, Brazil.
Cornea. 1998 Nov;17(6):607-10. doi: 10.1097/00003226-199811000-00007.
To study two cases of corneal scarring due to trauma (one case) and infection (one case) unrelated to a previous photorefractive keratectomy (PRK) for the correction of myopia.
The patients are part of an Institutional Review Board-approved study of the safety and efficacy of PRK. Both patients underwent bilateral, nonsimultaneous corneal ablation based on preoperative spherical equivalent.
Seven months after PRK, the first patient sustained an alkali burn in one eye that caused severe corneal scarring and myopic regression. The other patient developed bilateral keratoconjunctivitis, more intense in the right eye (1 month after the operation) than in the left eye (4 months after the operation). This right eye subsequently developed diffuse scarring and loss of visual acuity.
Patients who have undergone PRK may develop severe corneal scarring after relatively mild ocular traumas or infections.
研究两例因外伤（1例）和感染（1例）导致角膜瘢痕形成的病例，这两例与之前用于矫正近视的准分子激光原位角膜磨镶术（PRK）无关。
这些患者是机构审查委员会批准的一项关于PRK安全性和有效性研究的一部分。两名患者均根据术前等效球镜度数接受了双侧、非同时性角膜消融术。
PRK术后七个月，首例患者一只眼睛遭受碱烧伤，导致严重角膜瘢痕形成和近视回退。另一名患者发生双侧角结膜炎，右眼（术后1个月）比左眼（术后4个月）更严重。随后，右眼出现弥漫性瘢痕形成和视力丧失。
接受过PRK的患者在相对轻微的眼外伤或感染后可能会出现严重的角膜瘢痕形成。
