Yetman R J, Parks D K, Huseby V, Mistry K, Garcia J
Division of Community and General Pediatrics, University of Texas-Houston Medical School 77030, USA.
J Pediatr. 1998 Nov;133(5):705-7. doi: 10.1016/s0022-3476(98)70117-9.
A retrospective medical record review was completed for 264 consecutive newborns receiving phototherapy for hyperbilirubinemia to determine whether a "rebound" increase in total serum bilirubin (TSB) level occurs after termination of phototherapy. The difference between mean TSB levels at discontinuation of phototherapy and at rebound was calculated by paired t test. TSB levels at rebound were significantly lower than at discontinuation of phototherapy for infants weighing > 1800 g (positive and negative Coombs' test results). There were no statistically significant differences among infants in the smaller weight categories, regardless of Coombs' test results. Infants completing phototherapy for hyperbilirubinemia who are otherwise healthy do not require follow-up solely to identify a rebound bilirubin level.
对264例因高胆红素血症接受光疗的连续新生儿进行了回顾性病历审查，以确定光疗结束后血清总胆红素（TSB）水平是否会出现“反弹”升高。通过配对t检验计算光疗停止时和反弹时的平均TSB水平差异。对于体重>1800 g的婴儿（直接和间接抗人球蛋白试验结果），反弹时的TSB水平显著低于光疗停止时。无论抗人球蛋白试验结果如何，较小体重类别的婴儿之间均无统计学显著差异。因高胆红素血症完成光疗且无其他健康问题的婴儿，无需仅为确定胆红素反弹水平而进行随访。
