Berger G M, Cowlin J, Turner T J
S Afr Med J. 1976 Sep 18;50(40):1559-61.
The amylase:creatinine clearance ratio in patients suffering from acute pancreatitis or acute duodenal perforation was higher than normal in both groups of patients. These findings cast doubt on the value of this parameter as a specific index of acute pancreatitis. The mechanism or mechanisms underlying the increased amylase excretion have not been determined. However, the markedly elevated urinary excretion of lysozyme observed in some patients suggests, by analogy, that diminished tubular reabsorption of amylase may contribute towards the elevated amylase:creatinine ratio.
急性胰腺炎或急性十二指肠穿孔患者的淀粉酶与肌酐清除率在两组患者中均高于正常水平。这些发现使人对该参数作为急性胰腺炎特异性指标的价值产生怀疑。淀粉酶排泄增加的潜在机制尚未确定。然而，一些患者中观察到的溶菌酶尿排泄显著升高，由此类推，提示淀粉酶肾小管重吸收减少可能导致淀粉酶与肌酐比值升高。
