Rabah R, Kupsky W J, Haas J E
Department of Pathology and Laboratory Medicine, Children's Hospital of Michigan, Detroit 48201, USA.
Arch Pathol Lab Med. 1998 Nov;122(11):1030-3.
We report the case of an 11-month-old child with acquired immunodeficiency syndrome, who despite treatment for systemic candidiasis developed undetected Candida meningitis. This uncommon manifestation of candidiasis was accompanied by basilar granulomatous inflammation and fibrosis of meninges with arteritis, vascular invasion by fungi, and terminal subarachold hemorrhage. To our knowledge, this constellation of findings has not been reported previously in pediatric acquired immunodeficiency syndrome.
我们报告了一例11个月大的获得性免疫缺陷综合征患儿，尽管接受了系统性念珠菌病治疗，但仍发生了未被检测出的念珠菌性脑膜炎。这种念珠菌病的罕见表现伴有基底膜肉芽肿性炎症和脑膜纤维化，并伴有动脉炎、真菌血管侵袭和终末期蛛网膜下腔出血。据我们所知，这种一系列的表现此前在儿童获得性免疫缺陷综合征中尚未有过报道。
