Zieve L, Nicoloff D
Surgery. 1976 Nov;80(5):554-7.
Volatile free fatty acids (VFA) in blood increased approximately twofold in dogs subjected to total hepatectomy. The average total plasma VFA preoperatively was 1,585 mug percent and shortly before death, postoperatively, was 2,798 mug percent. The corresponding red cell concentrations were essentially the same. Acetic acid was 81 percent of the total VFA, propionic acid 7 percent, isobutyric acid 4 percent, butyric acid one percent, and isovaleric acid 5 percent. There was little or no isovalerate in red cells. The increments in the individual fatty acids after hepatectomy were highly variable, but the average increase with time was almost linear. The increase in VFA probably reflects an increased utilization of the branched-chain aminoacids by extrahepatic tissues.
接受全肝切除的犬血液中的挥发性游离脂肪酸（VFA）增加了约两倍。术前血浆VFA的平均总量为1585微克百分比，术后临近死亡时为2798微克百分比。相应的红细胞浓度基本相同。乙酸占总VFA的81%，丙酸占7%，异丁酸占4%，丁酸占1%，异戊酸占5%。红细胞中几乎没有异戊酸。肝切除术后各脂肪酸的增量变化很大，但随时间的平均增加几乎呈线性。VFA的增加可能反映了肝外组织对支链氨基酸的利用增加。
