Incesulu A, Nadol J B
Department of Otology and Laryngology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston 02114-3096, USA.
Ann Otol Rhinol Laryngol. 1998 Nov;107(11 Pt 1):906-11. doi: 10.1177/000348949810701102.
In a temporal bone study of 26 ears from 13 patients who, in life, had severe sensorineural hearing loss, the segmental and total spiral ganglion cell (SGC) counts were correlated with hearing thresholds and with the difference between hearing thresholds in the two ears, the age at death, the duration of deafness, and the duration of hearing loss. A statistically significant correlation was found between the interaural differences in total SGC counts and the interaural difference in pure tone averages for 3, 4, and 5 frequencies. The total SGC count was higher in the ear with the better residual hearing in 11 of 12 cases. Approximately 41% of the variability in interaural difference in pure tone average was explained by the difference in SGC counts. The findings would suggest that in a given individual, selection of the ear with better residual hearing for cochlear implantation is likely to result in accessing a higher number of residual SGCs. This, in turn, may result in better speech recognition with the implant.
在一项针对13名生前患有严重感音神经性听力损失患者的26只耳颞骨研究中，节段性和总的螺旋神经节细胞（SGC）计数与听力阈值、双耳听力阈值之差、死亡年龄、耳聋持续时间以及听力损失持续时间相关。在总的SGC计数的双耳差异与3、4和5个频率的纯音平均值的双耳差异之间发现了具有统计学意义的相关性。在12例中的11例中，残余听力较好的耳中的总SGC计数更高。纯音平均值双耳差异中约41%的变异性可由SGC计数差异解释。这些发现表明，在特定个体中，选择残余听力较好的耳进行人工耳蜗植入可能会接入更多的残余SGC。反过来，这可能会使植入后的语音识别更好。
