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乳腺癌根治术后淋巴水肿发病机制的研究

A study on the pathogenesis of postmastectomy lymphedema.

作者信息

Abe R

出版信息

Tohoku J Exp Med. 1976 Feb;118(2):163-71. doi: 10.1620/tjem.118.163.

DOI:10.1620/tjem.118.163
PMID:982430
Abstract

In order to study the causes of postmastectomy lymphedema, venography, lymphangiography and RISA absorption test were performed on the patients following radical mastectomy. Venous obstruction was a rare cause of postmastectomy lymphedema. Edema patterns in arm lymphangiography were observed in the patients with lymphedema and even in some of the non-edematous upper extremities. The finding of axillary lymphangiography was correlated with the degree of edema of the upper extremity. The absence of adequate lymphatic pathway across the axilla (type 2, collateral and type 3, blocking) was thought to provide the pathologic base for the postmastectomy lymphedema. RISA absorption test also provided precise information of the lymphatic flow in the extremity. It was lower in the patients with edema, as compared with the patients without edema.

摘要

为了研究乳房切除术后淋巴水肿的病因,对行根治性乳房切除术后的患者进行了静脉造影、淋巴管造影和放射性核素淋巴管造影吸收试验。静脉阻塞是乳房切除术后淋巴水肿的罕见病因。在有淋巴水肿的患者甚至一些无水肿的上肢中观察到了手臂淋巴管造影的水肿模式。腋窝淋巴管造影的结果与上肢水肿程度相关。认为腋窝处缺乏足够的淋巴通路(2型,侧支型和3型,阻塞型)为乳房切除术后淋巴水肿提供了病理基础。放射性核素淋巴管造影吸收试验也提供了肢体淋巴流动的精确信息。与无水肿患者相比,水肿患者的该指标较低。

相似文献

1
A study on the pathogenesis of postmastectomy lymphedema.乳腺癌根治术后淋巴水肿发病机制的研究
Tohoku J Exp Med. 1976 Feb;118(2):163-71. doi: 10.1620/tjem.118.163.
2
The role of lymphovenous communication in the development of postmastectomy lymphedema.
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[Lymphophlebographic studies in arm edema].
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[Anatomofunctional investigations of lymphatic circulation in the upper extremity by means of lymphangiography. Considerations on the etiopathogenetic bases of postmastectomy indurative edema].[通过淋巴管造影术对上肢淋巴循环进行解剖功能研究。关于乳房切除术后硬结性水肿的病因发病学基础的思考]
Ann Ital Chir. 1960;37:363-83.
5
The investigation of postmastectomy oedema of the arm by lymphography and venography.通过淋巴管造影术和静脉造影术对乳房切除术后手臂水肿的研究。
Clin Radiol. 1978 Jul;29(4):457-62. doi: 10.1016/s0009-9260(78)80111-1.
6
[Changes in the lymphatic vessels of the upper extremity following a radical mastectomy (based on lymphographic data)].
Vopr Onkol. 1986;32(2):23-8.
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Patterns of lymphatic drainage after axillary node dissection impact arm lymphoedema severity: A review of animal and clinical imaging studies.腋窝淋巴结清扫术后淋巴引流模式影响手臂淋巴水肿严重程度:动物及临床影像学研究综述
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[THE LYMPH CIRCULATION OF THE UPPER EXTREMITY FOLLOWING THE RADICAL OPERATION OF MAMMARY CANCER AND ITS RELATIONS TO THE SECONDARY EDEMA OF THE ARM].
Chirurg. 1964 Apr;35:145-8.
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Indocyanine green-enhanced lymphography for upper extremity lymphedema: a novel severity staging system using dermal backflow patterns.吲哚菁绿增强淋巴造影术在上肢淋巴水肿中的应用:一种新的基于皮肤回流模式的严重程度分期系统。
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Clinical experiences using pneumatic massage therapy for edematous limbs over the last 10 years.过去10年中使用气动按摩疗法治疗肢体水肿的临床经验。
Angiology. 1988 Feb;39(2):154-63. doi: 10.1177/000331978803900205.

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Pre-collecting lymphatic vessels form detours following obstruction of lymphatic flow and function as collecting lymphatic vessels.预收集淋巴管在淋巴流动和功能受阻后形成旁路,并作为收集淋巴管发挥作用。
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Impairment of lymph drainage in subfascial compartment of forearm in breast cancer-related lymphedema.乳腺癌相关淋巴水肿中前臂筋膜下间隙淋巴引流受损。
Lymphat Res Biol. 2003;1(2):121-32. doi: 10.1089/153968503321642615.