Manne S L, Du Hamel K, Gallelli K, Sorgen K, Redd W H
Fox Chase Cancer Center, Cheltenham, Pennsylvania 19012, USA.
J Pediatr Psychol. 1998 Dec;23(6):357-66. doi: 10.1093/jpepsy/23.6.357.
To examine posttraumatic stress disorder (PTSD) in mothers of survivors of childhood cancer. Comorbidity of anxiety and depressive disorders, prevalence of subclinical PTSD, and the utility of a self-report measure as a screening instrument for PTSD were also investigated.
Mothers (n = 65) completed a questionnaire self-report PTSD checklist (PCL-C). Mothers were administered several modules of the SCID: nonpatient edition by telephone, including the PTSD, Generalized Anxiety, and Major Depressive Disorder modules.
We diagnosed 6.2% of the sample with current PTSD. An additional 20% had subclinical PTSD. One of four mothers with PTSD diagnoses had a comorbid diagnosis of an anxiety and depressive disorder. The PCL-C evidenced diagnostic utility as a screening instrument. However, a moderate number of false-positives would result if the recommended cut-off on the instrument was used.
The PCL-C had diagnostic utility in screening mothers of childhood cancer survivors. The presence of comorbid diagnoses such as anxiety and depression should be examined.
研究儿童癌症幸存者母亲的创伤后应激障碍（PTSD）。同时调查焦虑和抑郁障碍的共病情况、亚临床PTSD的患病率，以及一种自我报告测量工具作为PTSD筛查工具的效用。
65名母亲完成了一份创伤后应激障碍自我报告清单（PCL-C）问卷。通过电话对母亲们进行了SCID：非患者版的几个模块的测试，包括创伤后应激障碍、广泛性焦虑和重度抑郁障碍模块。
我们诊断出6.2%的样本患有当前创伤后应激障碍。另外20%有亚临床创伤后应激障碍。在被诊断为创伤后应激障碍的母亲中，四分之一的人同时患有焦虑和抑郁障碍。PCL-C作为筛查工具具有诊断效用。然而，如果使用该工具推荐的临界值，会产生相当数量的假阳性结果。
PCL-C在筛查儿童癌症幸存者母亲方面具有诊断效用。应检查焦虑和抑郁等共病诊断的存在情况。
