Puolakkainen P, Kemppainen E, Leppäniemi A, Sainio V, Hietaranta A, Haapiainen R
Second Department of Surgery, Helsinki University Central Hospital, Finland.
Ann Chir Gynaecol. 1998;87(3):200-3.
The treatment of mild acute pancreatitis (AP) with fluid replacement and other conservative measures is adequate and sufficient in the majority of patients. The corner-stones of the treatment of patients with severe acute pancreatitis include early aggressive fluid resuscitation, intensive care with close monitoring and support of organ function, antibiotic prophylaxis, early supportive treatment of organ failure, and surgery in selected cases with infected pancreatic necrosis or deterioration of patient's condition in spite of maximal conservative therapy. Early endoscopic removal of common bile duct stones should be considered in cases with biliary AP. Altogether, increased accuracy in early diagnosis and development of intensive care have resulted in a significant decrease in mortality of patients with severe pancreatitis. In this paper, we review the current principles and methods of treatment in acute pancreatitis at Helsinki University Central Hospital.
对于大多数轻度急性胰腺炎（AP）患者，采用补液及其他保守措施进行治疗是足够且充分的。重症急性胰腺炎患者治疗的基石包括早期积极的液体复苏、密切监测和支持器官功能的重症监护、抗生素预防、器官功能衰竭的早期支持治疗，以及在某些感染性胰腺坏死或尽管采取了最大程度的保守治疗但患者病情仍恶化的情况下进行手术。对于胆源性AP病例，应考虑早期内镜下取出胆总管结石。总体而言，早期诊断准确性的提高和重症监护的发展已导致重症胰腺炎患者的死亡率显著下降。在本文中，我们回顾了赫尔辛基大学中心医院急性胰腺炎当前的治疗原则和方法。
