一些3-哌嗪基甲基-5-芳基-1H-1,2,4-三唑的合成、抗真菌活性及抗菌评价
Synthesis, antifungal activity and antibacterial evaluation of some 3-piperazinylmethyl-5-aryl-1H-1,2,4-triazoles.
作者信息
Papakonstantinou-Garoufalias S S, Todoulou O G, Filippatos E C, Papadaki-Valiraki A E, Chytiroglou-Lada A
机构信息
Department of Pharmacy, School of Medicine, University of Athens, Greece.
出版信息
Arzneimittelforschung. 1998 Oct;48(10):1019-23.
PMID:9825120
Abstract
Some new 3-piperazinylmethyl-5-aryl-1H-1,2,4-triazoles have been prepared and tested for their antifungal and antimicrobial activity. Among them, compounds 3g and 3h exhibited higher antifungal activity than ketoconazole against Cladosporium cladosporoides and Aspergillus niger respectively.
摘要
一些新的3-哌嗪基甲基-5-芳基-1H-1,2,4-三唑已被制备并测试其抗真菌和抗菌活性。其中，化合物3g和3h分别对枝孢霉菌和黑曲霉表现出比酮康唑更高的抗真菌活性。
Zotero 插件