Musshoff F, Kraemer T
Institute of Legal Medicine, Friedrich-Wilhelms-University, Bonn, Germany.
Int J Legal Med. 1998;111(6):305-8. doi: 10.1007/s004140050176.
After a traffic accident a 32-year-old man was suspected of having previously taken an illegal drug. An immunochemical screening procedure revealed positive results for amphetamines in both urine and blood samples. The preliminary test was confirmed by GC/MS and both amphetamine and methamphetamine were found in both body fluids. However, the man denied any use of drugs but claimed to have taken four tablets of Gewodin. One of the ingredients, famprofazone, undergoes metabolic conversion to amphetamine and methamphetamine. Using GC/ MS the ingestion of famprofazone was verified by identification of the unchanged parent compound in the urine sample.
一名32岁男子在交通事故后被怀疑此前服用了非法药物。免疫化学筛查程序显示其尿液和血液样本中的苯丙胺检测结果均为阳性。气相色谱/质谱联用仪(GC/MS)证实了初步检测结果,两种体液中均发现了苯丙胺和甲基苯丙胺。然而,该男子否认使用过任何药物,但声称服用了四片复方氨酚烷胺片。其中一种成分安替比林会代谢转化为苯丙胺和甲基苯丙胺。通过气相色谱/质谱联用仪(GC/MS)在尿液样本中鉴定出未发生变化的母体化合物,从而证实了安替比林的摄入。