Mahan G D, Engler W E, Tiemann J J, Uzgiris E
Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996, USA.
Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14015-9. doi: 10.1073/pnas.95.24.14015.
A theory is provided for the detection efficiency of diffuse light whose frequency is modulated by an acoustical wave. We derive expressions for the speckle pattern of the modulated light, as well as an expression for the signal-to-noise ratio for the detector. The aim is to develop a new imaging technology for detection of tumors in humans. The acoustic wave is focused into a small geometrical volume, which provides the spatial resolution for the imaging. The wavelength of the light wave can be selected to provide information regarding the kind of tumor.
提出了一种关于频率由声波调制的漫射光检测效率的理论。我们推导了调制光散斑图案的表达式以及探测器信噪比的表达式。目的是开发一种用于检测人体肿瘤的新成像技术。声波被聚焦到一个小的几何体积中,这为成像提供了空间分辨率。可以选择光波的波长以提供有关肿瘤类型的信息。