Thai Quang Minh, Kalot Ghadir, Venet Caroline, Seguin Johanne, Bocoum Maïmouna, Mignet Nathalie, Ramaz François, Louchet-Chauvet Anne
Institut Langevin, ESPCI Paris, Université PSL, CNRS, 1 rue Jussieu, 75005 Paris, France.
Université de Paris Cité, INSERM, CNRS, UTCBS, Faculté de Pharmacie, 4 avenue de l'Observatoire, 75006 Paris, France.
Biomed Opt Express. 2022 Nov 16;13(12):6484-6496. doi: 10.1364/BOE.475449. eCollection 2022 Dec 1.
We present ultrasound modulated optical tomography (UOT) results on mice, using the persistent spectral hole burning (PSHB) effect in a Tm:YAG crystal. Indocyanine green (ICG) solution was injected as an optical absorber and was clearly identified on the PSHB-UOT images, both in the muscle (following an intramuscular injection) and in the liver (following an intravenous injection). This demonstration also validates an experimental setup with an improved level of performance combined with an increased technological maturity compared to previous demonstrations.
我们展示了使用掺铥钇铝石榴石（Tm:YAG）晶体中的持久光谱烧孔（PSHB）效应在小鼠身上进行的超声调制光学层析成像（UOT）结果。注射吲哚菁绿（ICG）溶液作为光学吸收剂，在PSHB-UOT图像上，无论是在肌肉中（肌内注射后）还是在肝脏中（静脉注射后）都能清晰识别。与之前的演示相比，这次演示还验证了一种性能有所提高且技术成熟度有所提升的实验装置。
