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伴有和不伴有多发伤的重度颅脑损伤患者的预后。

Outcome in severely head injured patients with and without multiple trauma.

作者信息

Baltas I, Gerogiannis N, Sakellariou P, Matamis D, Prassas A, Fylaktakis M

机构信息

Department of Neurosurgery, G. Papanikolaou Hospital, Thessaloniki, Greece.

出版信息

J Neurosurg Sci. 1998 Jun;42(2):85-8.

PMID:9826792
Abstract

BACKGROUND

This work attempts to analyse the potential role of multiple injury in the outcome of non-shock severely head injured patients with a Glasgow Coma Scale (GCS) of 8 or less.

METHODS

386 non-shock adult patients of < 65 years (mean age 33.74 +/- 14.7), treated with the same therapeutic protocol, were studied retrospectively. Multiple traumatised patients classified into Injury Severity Scale (ISS) of < or = 9 and > 9. The ISS classification was also tested in two subgroups of patients with GCS 3-5 and GCS 6-8.

RESULTS

The overall mortality of the 386 patients was 22.79%. Those suffering from extracranial injuries (n = 146, 37.82%) and those without (n = 240), presented similar mortality (21.23% vs 23.75% respectively). The multiple traumatised victims presented mean ISS 9.3 +/- 8.17. Those with ISS > 9 had greater mortality than those with ISS < or = 9, but the difference was not statistically significant (p > 0.05). The influence of ISS was not also significant in the mortality, either patients were of GCS 3-5 or GCS 6-8.

CONCLUSIONS

Multiple trauma in non-shock patients, as it is expressed by ISS does not have any influence on mortality. Mortality is depending on the severity of the intracranial pathology. Perhaps head injury and extracranial injuries have synergistic effect on morbidity.

摘要

背景

本研究旨在分析多发伤在格拉斯哥昏迷量表(GCS)评分≤8分的非休克重型颅脑损伤患者预后中的潜在作用。

方法

回顾性研究386例年龄<65岁(平均年龄33.74±14.7岁)的非休克成年患者,所有患者均采用相同的治疗方案。将多发伤患者根据损伤严重程度评分(ISS)分为≤9分和>9分两组。ISS分类也在GCS评分为3 - 5分和6 - 8分的两个亚组患者中进行测试。

结果

386例患者的总死亡率为22.79%。有颅外损伤的患者(n = 146,37.82%)和无颅外损伤的患者(n = 240)死亡率相似(分别为21.23%和23.75%)。多发伤患者的平均ISS为9.3±8.17。ISS>9分的患者死亡率高于ISS≤9分的患者,但差异无统计学意义(p>0.05)。无论患者GCS评分为3 - 5分还是6 - 8分,ISS对死亡率的影响均不显著。

结论

以ISS表示的多发伤对非休克患者的死亡率无影响。死亡率取决于颅内病变的严重程度。或许颅脑损伤和颅外损伤对发病率有协同作用。

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