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[进行性坏疽性口炎:关于在瓦加杜古国家医院中心所见的27例病例]

[Progressive noma: apropos of 27 cases seen at the National Hospital Center of Ouagadougou].

作者信息

Ouoba K, Sanou I, Dao M, Kam L, Ouedraogo A, Ouedraogo R, Sawadogo A

机构信息

Service ORL, CHN Yalgado Ouédraogo, Ouagadougou, Burkina Faso.

出版信息

Dakar Med. 1998;43(1):45-8.

PMID:9827155
Abstract

This retrospective study objects to report epidemiological profile, clinical display and take care of progressive noma at the National Hospital Center of Ouagadougou. We assign the term noma to the gangrenous gingivo-stomatitis occurring in a prone environment, leading in a few days into a sharp ulcer in the soft parts, accompanied by halitosis. This definition excludes noma like-lesions. 27 cases have been observed in the ENT department and the Paediatrics between 1991 and 1995. They were 17 boys and 10 girls aging between 2 and 8 years and most of them coming from families with modest income (76%). The consultation delay averaged 8 days. The research for associated pathologies showed 63% energizing and protein malnutrition. We only observed unilateral localisations and no case of extra-facial one. At the stage we received our patients, the gangrenous was formed and the aspect evoked noma right away. Quite a lot needs to be done for precocious diagnosis because it is at the beginning phase that best evolution is obtained. Even though no evidence of the responsibility of a specific pathogenic germ was established so far, nevertheless, the assumption that has more support remains that of a bacterial infection in a prone environment. The vital prognosis of the progressive noma appears to be much linked with intensive care and feeding again. The hope to see this poverty-linked pathology under control is essentially based on prevention: medical population information, medical personnel's awareness for early diagnosis and best take care of these patients, improvement of the living conditions of the people and the health care services.

摘要

这项回顾性研究旨在报告瓦加杜古国家医院中心坏疽性口炎的流行病学特征、临床表现及治疗情况。我们将坏疽性口炎定义为在易感环境中发生的坏疽性龈口炎,数天内可发展为软组织的剧痛性溃疡,并伴有口臭。该定义排除了类似坏疽性口炎的病变。1991年至1995年间,在耳鼻喉科和儿科共观察到27例病例。患者为17名男孩和10名女孩,年龄在2至8岁之间,大多数来自低收入家庭(76%)。就诊延迟平均为8天。相关病理检查显示63%的患者存在能量和蛋白质营养不良。我们仅观察到单侧病变,未发现面部以外的病例。在接收患者时,坏疽已经形成,外观立即提示为坏疽性口炎。由于早期诊断能取得最佳疗效,因此在早熟诊断方面仍有许多工作要做。尽管目前尚未确定特定致病病原体的责任,但最有可能的假设仍是易感环境中的细菌感染。进行性坏疽性口炎的预后似乎与重症监护和再次喂养密切相关。控制这种与贫困相关疾病的希望主要基于预防:对民众进行医学宣传、提高医务人员对早期诊断和最佳治疗这些患者的认识、改善民众的生活条件以及医疗服务。

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