Marmont A M, van Lint M T, Occhini D, Lamparelli T, Bacigalupo A
II Division of Haematology and Stem Cell Transplantation Centre, S Martino's Hospital, Genova, Italy.
Bone Marrow Transplant. 1998 Oct;22(8):827-8. doi: 10.1038/sj.bmt.1701431.
A 44-year-old man with splenectomised refractory autoimmune thrombocytopenic purpura (AITP) of 10 years' duration underwent an autologous, T cell-depleted marrow transplant following conditioning with thiotepa and CY. There was no response to the transplant procedure. This is the fourth case in the literature to show failure following autologous stem cell transplantation, although complete, steroid-independent remissions were obtained in the first two patients for over 1 year.
一名44岁男性，患难治性自身免疫性血小板减少性紫癜（AITP）10年且已行脾切除术，在接受噻替派和环磷酰胺预处理后进行了自体T细胞去除骨髓移植。移植过程无反应。这是文献中第四例自体干细胞移植失败的病例，尽管前两名患者获得了超过1年的完全、不依赖类固醇的缓解。
