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精神分裂症中经验性缺陷的两个因素及其与阳性、阴性和抑郁症状的关系。

Two factors of experienced deficits in schizophrenia and their relationships with positive, negative, and depressive symptoms.

作者信息

Iwawaki A, Narushima K, Ota K, Okura T, Tsuchiya K, Takashima A

机构信息

Department of Neuropsychiatry, School of Medicine, Tokyo Medical and Dental University, Japan.

出版信息

Compr Psychiatry. 1998 Nov-Dec;39(6):386-91. doi: 10.1016/s0010-440x(98)90052-9.

DOI:10.1016/s0010-440x(98)90052-9
PMID:9829147
Abstract

Eighty inpatients and 20 outpatients with ICD-10 schizophrenia were assessed with the Manchester Scale (MS) and the scale for the assessment of Subjective Experience of Deficits in Schizophrenia (SEDS). A factor analysis on MS scores yielded a three-factor solution: negative symptoms, positive symptoms, and anxious-depressive factor. On the other hand, a factor analysis on SEDS scores provided a seven-factor solution. The first factor, "awareness of social incompetence (ASI)," positively correlated with the anxious-depressive factor. ASI may reflect a negative cognitive attitude of persons who easily become depressive. The second factor, "subjective cognitive disturbance (SCD)," positively correlated with the positive-symptoms factor. SCD might represent a subtle disturbance, which can also produce positive symptoms. We found no factor on SEDS that correlated with the negative-symptoms factor. It was noted that a selection and comparison of items and the cultural background of subjects should be considered.

摘要

对80名住院患者和20名患有国际疾病分类第十版(ICD - 10)精神分裂症的门诊患者,采用曼彻斯特量表(MS)和精神分裂症缺陷主观体验评估量表(SEDS)进行评估。对MS评分进行因子分析得到一个三因子解:阴性症状、阳性症状和焦虑抑郁因子。另一方面,对SEDS评分进行因子分析得到一个七因子解。第一个因子“社交无能意识(ASI)”与焦虑抑郁因子呈正相关。ASI可能反映了容易抑郁者的消极认知态度。第二个因子“主观认知障碍(SCD)”与阳性症状因子呈正相关。SCD可能代表一种细微的障碍,也可产生阳性症状。我们发现SEDS中没有与阴性症状因子相关的因子。需要注意的是,应考虑项目的选择和比较以及受试者的文化背景。

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