Vopr Pitan. 1976 Sep-Oct(5):29-34.
In acute and chronic tests with dogs the effect of feeding the animals on meat, bread, or butter upon the pancreatic enzymes incretion was studied. The activity of the amylase, lipase, trypsin and of its inhibitor was determined during an acute test in the thoracic duct lymph, in the blood plasma of the portal and jugular veins, the amylase and lipase being also determined in the urine. The incretion of the pancreatic enzymes is adapted to the type of the food stimulant, viz. after feeding on bread it is the amylase incretion that increases to the most, on meat--it is that of trypsin and its inhibitor and on butter - of lipase. Most informative as to the level of the hydrolases increation adaptability is separation of corresponding enzymes forming part of the lymph, less so - their content in the plasma of the portal and still less - in the peripheral venous blood and the least - the content and segregation of the hydrolases from the urine.
在对狗进行的急性和慢性试验中,研究了给动物喂食肉类、面包或黄油对胰腺酶分泌的影响。在急性试验期间,测定了胸导管淋巴液、门静脉和颈静脉血浆中淀粉酶、脂肪酶、胰蛋白酶及其抑制剂的活性,同时也测定了尿液中的淀粉酶和脂肪酶。胰腺酶的分泌适应于食物刺激物的类型,即:喂食面包后,淀粉酶分泌增加最多;喂食肉类后,胰蛋白酶及其抑制剂分泌增加;喂食黄油后,脂肪酶分泌增加。关于水解酶分泌适应性水平,最具信息价值的是形成淋巴液一部分的相应酶的分离情况,其次是它们在门静脉血浆中的含量,在周围静脉血中的含量更少,而从尿液中水解酶的含量和分离情况所提供的信息最少。