Hale L P, Smith K, Braden G A, Owen J
Section on Hematology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.
Cathet Cardiovasc Diagn. 1998 Nov;45(3):318-22. doi: 10.1002/(sici)1097-0304(199811)45:3<318::aid-ccd23>3.0.co;2-2.
Heparin is considered necessary during percutaneous coronary interventions; however, heparin is contraindicated in patients with heparin-induced thrombocytopenia and/or heparin antibodies. We describe the successful use of the heparinoid Orgaran (danaparoid sodium) in addition to abciximab (ReoPro) in a patient with heparin antibodies who required rotational atherectomy.
在经皮冠状动脉介入治疗期间,肝素被认为是必需的;然而,肝素在肝素诱导的血小板减少症和/或存在肝素抗体的患者中是禁忌的。我们描述了在一名需要旋磨术且存在肝素抗体的患者中,除了使用阿昔单抗(ReoPro)之外,成功使用类肝素药物Orgaran(达那肝素钠)的情况。