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[衣原体在人类慢性肾脏和泌尿生殖系统疾病中的作用]

[Role of chlamydia in chronic renal and urogenital diseases in man].

作者信息

Terskikh I I, Dzhavad-Zade M D, Kakhramanov T B, Popova O M, Babirov G I

出版信息

Vopr Virusol. 1976 May-Jun(3):345-50.

PMID:983001
Abstract

Serological examinations by the CFT with the group-specific ornithosis antigen were carried out with 1910 sera from patients with chronic diseases of the kidneys, urinary tracts and male sexual organs, as well as with 556 control sera from patients with cardio-vascular and other diseases for elucidation of the role of chlamydia (OLT group) in the infectious pathology of the kidneys and urinary tracts of man. No complement-fixing antibody was detected with the group-specific ornithosis antigen in control sera. The antibody was found in 5.2% of sera from patients with chronic diseases of the kidneys and upper urinary tracts and in 6.2% of cases with the involvement of the proximal part of the urinary tracts and male sexual organs. The intradermal test (IDT) with ornithosis allergen was performed for those patients whose sera contained complement-fixing antibody. The results of CFT and IDT coincided in 82.8% of the patients, thus confirming the etiological role of chlamydia in human urogenital pathology. Studies on the positive sera with the species-specific ornithosis antigen gave negative results, indicating that a distinct species of chlamydia is the agent of urogenital diseases.

摘要

采用补体结合试验(CFT),使用嗜衣原体病群特异性抗原,对1910份来自患有肾脏、尿路和男性性器官慢性疾病患者的血清,以及556份来自患有心血管疾病和其他疾病患者的对照血清进行检测,以阐明衣原体(OLT组)在人类肾脏和尿路传染性病理学中的作用。在对照血清中未检测到针对嗜衣原体病群特异性抗原的补体结合抗体。在患有肾脏和上尿路慢性疾病患者的血清中,5.2%检测到该抗体;在尿路近端及男性性器官受累的病例中,6.2%检测到该抗体。对血清中含有补体结合抗体的患者进行了嗜衣原体病变应原皮内试验(IDT)。补体结合试验和皮内试验结果在82.8%的患者中一致,从而证实了衣原体在人类泌尿生殖系统病理学中的病因学作用。用嗜衣原体病种特异性抗原对阳性血清进行检测,结果为阴性,表明一种独特的衣原体是泌尿生殖系统疾病的病原体。

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1
[Role of chlamydia in chronic renal and urogenital diseases in man].[衣原体在人类慢性肾脏和泌尿生殖系统疾病中的作用]
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[Role of Chylamydia in the pathology of pregnancy and chronic gynecological diseases].[衣原体在妊娠病理学和慢性妇科疾病中的作用]
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