DeSantiago S, Halhalí A, Perea F, Alonso L, Jasso F, Isoard F
Departamento de Fisiología de la Nutrición Salvador Zubirán, Instituto Nacional de la Nutrición, México D.F.
Rev Invest Clin. 1998 Jul-Aug;50(4):293-300.
To compare the balance of calcium (Ca) and phosphorus (P) between lactation and weaning, and to determine the Ca and P milk production in Mexican rural lactating women.
Thirty-six women aged 18-36 y, weight 49 +/- 3 kg and height 148 +/- 2 cm, were divided in six groups: four groups of lactation (1st, 3rd, 6th and 12th month) one post-weaning group and one of non pregnant non lactating women. The balance studies were performed collecting duplicate diets, 24 h urine for 3 days, 72 h feces and 24 h milk samples for 2 days. The Ca content was determined by atomic absorption spectrophotometry and P by the molybdate method.
Ca content in milk was higher in the 3rd month of lactation. The Ca balances were negative in all lactation groups (789 +/- 165 mg/d). Ca urinary excretion was lower in the lactating group (p < 0.05) suggesting a regulatory mechanism to conserve Ca during lactation. No differences were observed in the P content in milk and positive balances of P were observed in the non lactating and the post-weaning groups, whereas they were negative in the lactation groups (115 to 475 mg/d). High fecal Ca and P excretion (approximately 1300 mg/d) was observed, which contributed to the negative condition of the balance during lactation. The production of Ca and P in the milk of these rural women was similar to the one seen in rural and urban groups in Africa, Asia, Europe and the U.S.
比较哺乳期和断奶期钙(Ca)和磷(P)的平衡情况,并确定墨西哥农村哺乳期妇女的钙和磷产奶量。
36名年龄在18 - 36岁、体重49±3kg、身高148±2cm的女性被分为六组:四组哺乳期(第1、3、6和12个月)、一组断奶后组和一组非孕非哺乳期妇女。通过收集重复饮食、3天的24小时尿液、72小时粪便和2天的24小时乳汁样本进行平衡研究。钙含量通过原子吸收分光光度法测定,磷含量通过钼酸盐法测定。
哺乳期第3个月乳汁中的钙含量较高。所有哺乳期组的钙平衡均为负值(789±165mg/d)。哺乳期组的尿钙排泄较低(p<0.05),表明哺乳期存在一种保存钙的调节机制。乳汁中的磷含量未观察到差异,非哺乳期和断奶后组观察到磷的正平衡,而哺乳期组为负平衡(115至475mg/d)。观察到粪便中钙和磷的高排泄量(约1300mg/d),这导致了哺乳期平衡的负值状态。这些农村妇女乳汁中钙和磷的产量与非洲、亚洲、欧洲和美国农村及城市组的情况相似。