Aschoff A J, Seifarth H, Fleiter T, Sokiranski R, Görich J, Merkle E M, Wunderlich A P, Brambs H J, Zenkel M E
Abteilung für Diagnostische Radiologie, Universitätsklinikum Ulm.
Radiologe. 1998 Oct;38(10):810-5. doi: 10.1007/s001170050428.
This pilot study investigated the feasibility and clinical value of high-resolution virtual real-time laryngoscopy based on helical CT data sets. Nine patients with laryngeal pathology (three with tumors of the vocal cords, two laryngeal carcinomas, one with invasion of the larynx by thyroid carcinoma and six subglottic stenoses) underwent examination by helical CT at a collimation of 1 mm. Following acquisition, the images were processed at a workstation with standard visualization software, such that virtual endoscopy (VE) in real time was possible. The images were then compared with the findings of conventional endoscopy. Because of swallowing artifacts, reconstruction failed in 2 of 12 patients. None of the carcinomas of the vocal cords was recognized at VE or in the cross-sectional CT images. VE provided the correct diagnosis in 8 of 12 cases (laryngeal tumors, subglottic stenoses). Virtual laryngoscopy is capable of simulating the visual findings of endoscopy in cases of laryngeal tumors and subglottic stenoses. Small tumors of the vocal cords are not adequately visualized. The major problem affecting results is motion artifacts resulting from involuntary swallowing.
这项初步研究调查了基于螺旋CT数据集的高分辨率虚拟实时喉镜检查的可行性和临床价值。9例喉部病变患者（3例声带肿瘤、2例喉癌、1例甲状腺癌侵犯喉部和6例声门下狭窄）接受了准直为1mm的螺旋CT检查。采集后，图像在工作站使用标准可视化软件进行处理，从而实现实时虚拟内镜检查（VE）。然后将图像与传统内镜检查结果进行比较。由于吞咽伪影，12例患者中有2例重建失败。在VE或横断面CT图像中均未识别出任何声带癌。VE在12例病例中的8例（喉部肿瘤、声门下狭窄）中提供了正确诊断。虚拟喉镜能够模拟喉部肿瘤和声门下狭窄病例中的内镜视觉发现。声带小肿瘤显示不充分。影响结果的主要问题是不自主吞咽导致的运动伪影。
