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尸检材料中的静脉血栓形成与肺栓塞(作者译)

[Venous thromboses and pulmonary emboli in autopsy material (author's transl)].

作者信息

Schwarz N, Feigl W, Neuwirth E, Holzner J H

出版信息

Wien Klin Wochenschr. 1976 Jun 25;88(13):423-8.

PMID:983069
Abstract

Venous thromboses of the pelvic veins and the veins of the lower limbs were found in 40% of the post mortems carried out on 1350 adults during 1974. The thromboses were bilaterally located in the calf veins in the vast majority of cases. The predominating underlying diseases of patients with thrombosis were malignant neoplasia or cardiovascular diseases. 319 cases (23.5%) showed massive pulmonary embolism. The pulmonary embolism had taken a fulminating fatal course in 7.8% of cases. Thromboses of the lower limb veins seem to have a higher tendency to become mobilized to cause fatal pulmonary embolism than thromboses occurring in other sites. A significantly higher incidence of venous thrombosis, as well as of pulmonary embolism, was found in higher age groups and in female patients; the prognosis is, moreover, grave in these cases. A significant increase in the incidence of venous thromboses and pulmonary embolism-especially those with a rapidly fatal course-has been registered over the past years as compared with previous investigations.

摘要

在1974年对1350名成年人进行的尸检中,40%发现有盆腔静脉和下肢静脉血栓形成。在绝大多数病例中,血栓双侧位于小腿静脉。血栓形成患者的主要基础疾病是恶性肿瘤或心血管疾病。319例(23.5%)出现大面积肺栓塞。7.8%的病例中,肺栓塞呈暴发性致命病程。与其他部位发生的血栓相比,下肢静脉血栓似乎更易脱落导致致命性肺栓塞。在高龄组和女性患者中,静脉血栓形成以及肺栓塞的发生率显著更高;此外,这些病例的预后严重。与以往的调查相比,过去几年中静脉血栓形成和肺栓塞的发生率显著增加,尤其是那些病程迅速致命的病例。

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