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对硫磷中毒所致中间综合征合并迟发性远端多发性神经病

Intermediate syndrome with delayed distal polyneuropathy from ethyl parathion poisoning.

作者信息

Nisse P, Forceville X, Cezard C, Ameri A, Mathieu-Nolf M

机构信息

Centre Anti-Poisons de Lille, Centre Hospitalier Regional Universitaire de Lille, France.

出版信息

Vet Hum Toxicol. 1998 Dec;40(6):349-52.

PMID:9830697
Abstract

An acute poisoning in a 44-y-old female who ingested 50 ml of ethyl parathion concentrate (25 g) is described. She was treated by gastric lavage, administration of pralidoxime and atropine, and mechanical ventilation. As signs of intoxication disappeared at day 3, treatment was discontinued. The patient had a relapse of acute cholinergic crisis at day 4, and the same treatment was applied again. The acute poisoning phase was followed by an intermediate syndrome and delayed distal polyneuropathy. The clinical course of this severe ethyl parathion poisoning was favorable after 40 d.

摘要

本文描述了一名44岁女性急性中毒事件,该患者摄入了50毫升对硫磷浓缩液(25克)。她接受了洗胃、使用解磷定和阿托品治疗以及机械通气。由于中毒症状在第3天消失,治疗停止。患者在第4天出现急性胆碱能危象复发,再次采用相同治疗。急性中毒阶段之后出现了中间综合征和迟发性远端多发性神经病。40天后,此次严重对硫磷中毒的临床病程转好。

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