Pall H, Kleinberger G, Kotzaurek R, Pichler M, Szeless S
Wien Klin Wochenschr. 1976 Apr 2;88(7):246-8.
The hypertensive action of angiotensin is purely brought about by peripheral vasoconstriction and may, thus, lead to reduced perfusion of vital organs, especially the kidneys. The dangers of angiotensin in triggering off acute renal failure are illustrated by a case report in which this drug was administered to a comatose patient with hypovolaemic hypotension following barbiturate self-poisoning.
血管紧张素的升压作用完全是由外周血管收缩引起的,因此可能导致重要器官,尤其是肾脏的灌注减少。有一份病例报告说明了血管紧张素引发急性肾衰竭的危险性,该报告讲述了一名因服用巴比妥类药物自杀中毒而出现低血容量性低血压的昏迷患者使用了这种药物。