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心血管手术用不可吸收单丝缝线的体外性能测试开发与评估

Development of in vitro performance tests and evaluation of nonabsorbable monofilament sutures for cardiovascular surgery.

作者信息

Hong T, King M W, Michielsen S, Cheung L W, Mary C, Guzman R, Guidoin R

机构信息

Department of Clothing and Textiles, Faculty of Human Ecology, University of Manitoba, Winnipeg, Canada.

出版信息

ASAIO J. 1998 Nov-Dec;44(6):776-85. doi: 10.1097/00002480-199811000-00004.

DOI:10.1097/00002480-199811000-00004
PMID:9831085
Abstract

There have been reports suggesting that polypropylene (PP) monofilament sutures are associated with mechanical failure. To overcome this problem, a new monofilament suture made from polyvinylidene fluoride, under the trade name of Teflene, has been developed. Few studies have measured the in vitro properties of Teflene sutures, and those that have, have been limited to a few tensile properties of the straight suture such as tensile strength, elongation, and creep behavior. The in vitro performance properties of Teflene sutures were evaluated and compared with those of commercial sutures made from PP such as Prolene and Surgilene in four sizes, 2-0, 3-0, 4-0, and 5-0. The performance properties of sutures included both the physical properties of straight sutures, such as suture diameter, tensile strength, elongation, surface roughness, coefficient of friction, bending stiffness, and tissue drag, and the knot characteristics, such as knot pull strength, knot run-down, and knot security. Existing standard test methods and testing instruments were used if available to measure certain suture properties such as diameter, tensile strength, knot pull strength, and some physical properties. The other novel test methods and unique accessory devices needed to perform the tests for measuring tissue drag, knot run-down, coefficient of friction, and knot security were developed in the authors' laboratories, and the comparative results are reported for the first time. From the test results, Teflene sutures were found in general to possess equivalent characteristics to those of existing PP commercial sutures, but some differences also were observed, such as greater elongation and less knot run-down. These differences may give them a unique feel and handling performance, especially in terms of making a knot, sliding it into position, and causing less damage to adjacent tissue.

摘要

有报道表明聚丙烯(PP)单丝缝线与机械故障有关。为克服这一问题,已开发出一种由聚偏二氟乙烯制成的新型单丝缝线,商品名为特氟纶(Teflene)。很少有研究测量特氟纶缝线的体外性能,即便有研究,也仅限于直缝线的一些拉伸性能,如拉伸强度、伸长率和蠕变行为。对特氟纶缝线的体外性能进行了评估,并与四种尺寸(2-0、3-0、4-0和5-0)的由PP制成的商业缝线(如普理灵(Prolene)和舒吉伦(Surgilene))的性能进行了比较。缝线的性能既包括直缝线的物理性能,如缝线直径、拉伸强度、伸长率、表面粗糙度、摩擦系数、弯曲刚度和组织阻力,也包括打结特性,如结拉力、结下滑和结安全性。如有可用的现有标准测试方法和测试仪器,则用于测量某些缝线性能,如直径、拉伸强度、结拉力和一些物理性能。作者实验室开发了用于测量组织阻力、结下滑、摩擦系数和结安全性测试所需的其他新颖测试方法和独特辅助装置,并首次报告了比较结果。从测试结果来看,总体上发现特氟纶缝线具有与现有PP商业缝线相当的特性,但也观察到一些差异,如伸长率更高和结下滑更少。这些差异可能赋予它们独特的手感和操作性能,特别是在打结、将结滑到合适位置以及对相邻组织造成较少损伤方面。

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