Stefanadis C, Dernellis J, Lambrou S, Toutouzas P
Department Cardiology, Hippokration Hospital, University of Athens, Greece.
Am J Cardiol. 1998 Nov 15;82(10):1220-3. doi: 10.1016/s0002-9149(98)00610-9.
In a population consisting of 45 subjects (15 patients with mitral stenosis, 15 patients with heart failure, and 15 normal subjects), the left atrial (LA) pressure-area relation was assessed and the correlations between LA stroke work, LA kinetic energy, and LA ejection force were studied. The area of the counterclockwise A loop expressing the LA external work was measured. LA kinetic energy was obtained from the formula: 1/2 x stroke volume x 1.06 x v2, where v = transmitral Doppler A velocity. An excellent correlation was found between LA stroke work index and LA kinetic energy when data from all patients were plotted together (r = 0.95, p <0.001). The Pearson's correlation similarity coefficient between LA ejection force and kinetic energy as well as between LA ejection force and stroke work index was r = 0.54 (p <0.001). The r value of 0.54 was significantly lower than r = 0.95 (p <0.03). LA kinetic energy extends the use of transmitral flow Doppler data to include assessment of LA work. LA work can be obtained noninvasively with a high degree of accuracy.
在一个由45名受试者组成的群体中（15名二尖瓣狭窄患者、15名心力衰竭患者和15名正常受试者），评估了左心房（LA）压力-面积关系，并研究了LA每搏功、LA动能和LA射血力之间的相关性。测量了表示LA外部功的逆时针A环的面积。LA动能通过以下公式获得：1/2×每搏量×1.06×v2，其中v =经二尖瓣多普勒A速度。当将所有患者的数据绘制在一起时，发现LA每搏功指数与LA动能之间存在极好的相关性（r = 0.95，p <0.001）。LA射血力与动能之间以及LA射血力与每搏功指数之间的Pearson相关相似系数为r = 0.54（p <0.001）。0.54的r值显著低于r = 0.95（p <0.03）。LA动能扩展了经二尖瓣血流多普勒数据的应用范围，以包括对LA功的评估。LA功可以通过无创方式高精度地获得。
