Sylaidis P, O'Neill T J
Department of Plastic and Reconstructive Surgery, Norfolk and Norwich Hospital, United Kingdom.
Cleft Palate Craniofac J. 1998 Nov;35(6):544-5. doi: 10.1597/1545-1569_1998_035_0544_dafcps_2.3.co_2.
This prospective study looked at the postoperative hemorrhage risk associated with the use of diclofenac following cleft palate repair.
Twenty consecutive children (6 months to 9 years of age) requiring repair of the hard or soft palate were included.
Single per rectum doses of diclofenac were given at 1 mg/kg following cleft palate repair, with additional doses every 12 hours.
The use of the nonsteroidal anti-inflammatory drug, diclofenac, for postoperative analgesia is well established for many types of surgery. The authors find that twice daily diclofenac rectal suppositories provide very good analgesia postcleft palate repair. This, combined with supplemental oral paracetamol, obviates the need for opiates, resulting in alert infants who feed well and are suitable for early discharge.
本前瞻性研究观察腭裂修复术后使用双氯芬酸的出血风险。
纳入连续20例需要修复硬腭或软腭的儿童(6个月至9岁)。
腭裂修复术后按每千克体重1毫克的剂量经直肠给予单次双氯芬酸,每12小时追加一次剂量。
非甾体抗炎药双氯芬酸用于多种手术的术后镇痛已得到充分证实。作者发现,每日两次使用双氯芬酸直肠栓剂可为腭裂修复术后提供非常好的镇痛效果。这与补充口服对乙酰氨基酚相结合,无需使用阿片类药物,从而使婴儿保持清醒,喂养良好,适合早期出院。