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正常模式红宝石激光治疗对毛囊的选择性光热解作用。

Selective photothermolysis of hair follicles by normal-mode ruby laser treatment.

作者信息

Walther T, Bäumler W, Wenig M, Landthaler M, Hohenleutner U

机构信息

Department of Dermatology, University of Regensburg, Germany.

出版信息

Acta Derm Venereol. 1998 Nov;78(6):443-4. doi: 10.1080/000155598442755.

Abstract

This study was designed to evaluate the effect of selective photothermolysis on dark pigmented hair follicles treated with a normal-mode ruby laser (694-nm wavelength, pulse duration 0.5 ms, fluence 20 J/cm2, spot size 2 mm). In 15 volunteers, four test areas each were selected. After shaving, the first area was irradiated once, the second twice, the third three times and the fourth served as control area. A punch biopsy was taken from each volunteer immediately after the first laser treatment. Four weeks after the last irradiation, no effect was found in six cases and little effect in another six cases (50-90% regrowth). Hair regrowth of less than 30% was observed in only three cases. Eight weeks after the last session, no effect was found in 11 cases, little effect in 2 cases (10%) and less than 30% regrowth in only 2 cases. Twelve weeks after the last treatment, no difference could be detected between the areas untreated and treated by laser. The laser parameters applied in this study do not result in effective epilation of body hair. In some cases, a delay in growth of several weeks was noticed.

摘要

本研究旨在评估正常模式红宝石激光(波长694纳米,脉冲持续时间0.5毫秒,能量密度20焦/平方厘米,光斑大小2毫米)对深色毛囊进行选择性光热解的效果。在15名志愿者身上,各选取四个测试区域。剃毛后,第一个区域照射一次,第二个区域照射两次,第三个区域照射三次,第四个区域作为对照区域。在首次激光治疗后,立即从每位志愿者身上取一块钻孔活检组织。最后一次照射四周后,6例未见效果,另外6例效果不佳(毛发再生50 - 90%)。仅3例观察到毛发再生少于30%。最后一次治疗八周后,11例未见效果,2例效果不佳(10%),仅2例毛发再生少于30%。最后一次治疗十二周后,未治疗区域和激光治疗区域之间未检测到差异。本研究中应用的激光参数不能有效去除体毛发。在某些情况下,注意到毛发的生长延迟了几周。

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