Vaudaux B, Wimmersberger A
Schweizerische Kommission für Impffragen, Lausanne.
Soz Praventivmed. 1998;43 Suppl 1:S69-71, S143-5. doi: 10.1007/BF02042180.
The Swiss Federal Office of Public Health and the Swiss Advisory Board on Immunisation recommended that universal vaccination against hepatitis B be introduced in January 1998. The target population for immunisation are youngsters between 11 and 15 years of age. This recommendation does not preclude ongoing selective vaccination of individuals in high risk groups, nor the routine immunisation of individuals younger or older than the target age (if needed). Injections should be given in the deltoïd area and needle length is critical to ensure proper resorption of the antigen and adequate immune response. Three doses are recommended at times 0, 1 month and 6 months with no booster dose. The time interval between the second and third dose should not be shorter than 2 months but can be longer than 5 months. Vaccination initiated with one commercial brand can be completed with a different brand. The simultaneous administration of immune globulin with the initiation of vaccination and the measurement of serum antibodies after completion of vaccination are unnecessary.
瑞士联邦公共卫生局和瑞士免疫咨询委员会建议于1998年1月开始推行乙型肝炎普遍接种疫苗。免疫接种的目标人群是11至15岁的青少年。这项建议并不排除对高危人群持续进行选择性接种疫苗，也不排除对目标年龄之外的年轻人或年长者进行常规免疫接种（如有需要）。注射应在三角肌区域进行，针头长度对于确保抗原的适当吸收和充分的免疫反应至关重要。建议在0月、1个月和6个月时接种三剂，无需加强剂量。第二剂和第三剂之间的时间间隔不应短于2个月，但可长于5个月。开始用一个商业品牌进行的疫苗接种可以用不同品牌完成。在开始接种疫苗时同时给予免疫球蛋白以及在完成疫苗接种后测量血清抗体并无必要。
